Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles

Structures of BG505 SOSIP.664 trimer in complex with broadly neutralizing antibodies (bNAbs) have revealed the critical role of trimeric context for immune recognition of HIV-1. Presentation of trimeric HIV-1 antigens on nanoparticles may thus provide promising vaccine candidates. Here we report the...

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Detalles Bibliográficos
Autores principales: He, Linling, de Val, Natalia, Morris, Charles D., Vora, Nemil, Thinnes, Therese C., Kong, Leopold, Azadnia, Parisa, Sok, Devin, Zhou, Bin, Burton, Dennis R., Wilson, Ian A, Nemazee, David, Ward, Andrew B., Zhu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931238/
https://www.ncbi.nlm.nih.gov/pubmed/27349934
http://dx.doi.org/10.1038/ncomms12041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931238/
https://www.ncbi.nlm.nih.gov/pubmed/27349934
http://dx.doi.org/10.1038/ncomms12041

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