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A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries

Traumatic brain injury (TBI) is a major health and socio-economic problem, but no pharmacological agent is currently approved for the treatment of acute TBI. Thus, there is a great need for advances in this field. Here, we describe a short peptide (sequence CAQK) identified by in vivo phage display...

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Detalles Bibliográficos
Autores principales: Mann, Aman P., Scodeller, Pablo, Hussain, Sazid, Joo, Jinmyoung, Kwon, Ester, Braun, Gary B., Mölder, Tarmo, She, Zhi-Gang, Kotamraju, Venkata Ramana, Ranscht, Barbara, Krajewski, Stan, Teesalu, Tambet, Bhatia, Sangeeta, Sailor, Michael J., Ruoslahti, Erkki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931241/
https://www.ncbi.nlm.nih.gov/pubmed/27351915
http://dx.doi.org/10.1038/ncomms11980