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Comprehensive identification of internal structure and alternative splicing events in circular RNAs

Although previous studies demonstrated circular RNAs (circRNAs) does not exclusively comprise mRNA exons, no study has extensively explored their internal structure. By combining an algorithm with long-read sequencing data and experimental validation, we, for the first time, comprehensively investig...

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Detalles Bibliográficos
Autores principales: Gao, Yuan, Wang, Jinfeng, Zheng, Yi, Zhang, Jinyang, Chen, Shuai, Zhao, Fangqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931246/
https://www.ncbi.nlm.nih.gov/pubmed/27350239
http://dx.doi.org/10.1038/ncomms12060