The decision‐making process and criteria in selecting candidate drugs for progeria clinical trials

Hutchinson–Gilford progeria syndrome (progeria) is an extremely rare premature aging disease with a population prevalence of 1 in 20 million. Nevertheless, propelled by the discovery of a causal mutation in the lamin A/C gene (LMNA) (De Sandre‐Giovannoli et al, 2003; Eriksson et al, 2003) and strong...

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Detalles Bibliográficos
Autores principales: Gordon, Leslie B, Kieran, Mark W, Kleinman, Monica E, Misteli, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931284/
https://www.ncbi.nlm.nih.gov/pubmed/27234439
http://dx.doi.org/10.15252/emmm.201606280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931284/
https://www.ncbi.nlm.nih.gov/pubmed/27234439
http://dx.doi.org/10.15252/emmm.201606280

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