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A novel thermoregulatory role for PDE10A in mouse and human adipocytes

Phosphodiesterase type 10A (PDE10A) is highly enriched in striatum and is under evaluation as a drug target for several psychiatric/neurodegenerative diseases. Preclinical studies implicate PDE10A in the regulation of energy homeostasis, but the mechanisms remain unclear. By utilizing small‐animal P...

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Detalles Bibliográficos
Autores principales: Hankir, Mohammed K, Kranz, Mathias, Gnad, Thorsten, Weiner, Juliane, Wagner, Sally, Deuther‐Conrad, Winnie, Bronisch, Felix, Steinhoff, Karen, Luthardt, Julia, Klöting, Nora, Hesse, Swen, Seibyl, John P, Sabri, Osama, Heiker, John T, Blüher, Matthias, Pfeifer, Alexander, Brust, Peter, Fenske, Wiebke K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931292/
https://www.ncbi.nlm.nih.gov/pubmed/27247380
http://dx.doi.org/10.15252/emmm.201506085