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CUEDC2 modulates cardiomyocyte oxidative capacity by regulating GPX1 stability

The irreversible loss of cardiomyocytes due to oxidative stress is the main cause of heart dysfunction following ischemia/reperfusion (I/R) injury and ageing‐induced cardiomyopathy. Here, we report that CUEDC2, a CUE domain‐containing protein, plays a critical role in oxidative stress‐induced cardia...

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Detalles Bibliográficos
Autores principales: Jian, Zhao, Liang, Bing, Pan, Xin, Xu, Guang, Guo, Sai‐Sai, Li, Ting, Zhou, Tao, Xiao, Ying‐Bin, Li, Ai‐Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931293/
https://www.ncbi.nlm.nih.gov/pubmed/27286733
http://dx.doi.org/10.15252/emmm.201506010