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LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development

The Hippo pathway regulates the self-renewal and differentiation of various adult stem cells, but its role in cell fate determination and differentiation during liver development remains unclear. Here we report that the Hippo pathway controls liver cell lineage specification and proliferation separa...

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Detalles Bibliográficos
Autores principales: Lee, Da-Hye, Park, Jae Oh, Kim, Tae-Shin, Kim, Sang-Kyum, Kim, Tack-hoon, Kim, Min-chul, Park, Gun Soo, Kim, Jeong-Hwan, Kuninaka, Shinji, Olson, Eric N., Saya, Hideyuki, Kim, Seon-Young, Lee, Ho, Lim, Dae-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931324/
https://www.ncbi.nlm.nih.gov/pubmed/27358050
http://dx.doi.org/10.1038/ncomms11961