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LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development
The Hippo pathway regulates the self-renewal and differentiation of various adult stem cells, but its role in cell fate determination and differentiation during liver development remains unclear. Here we report that the Hippo pathway controls liver cell lineage specification and proliferation separa...
Autores principales: | Lee, Da-Hye, Park, Jae Oh, Kim, Tae-Shin, Kim, Sang-Kyum, Kim, Tack-hoon, Kim, Min-chul, Park, Gun Soo, Kim, Jeong-Hwan, Kuninaka, Shinji, Olson, Eric N., Saya, Hideyuki, Kim, Seon-Young, Lee, Ho, Lim, Dae-Sik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931324/ https://www.ncbi.nlm.nih.gov/pubmed/27358050 http://dx.doi.org/10.1038/ncomms11961 |
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