Targeting cell death signalling in cancer: minimising ‘Collateral damage'

Targeting apoptosis for the treatment of cancer has become an increasingly attractive strategy, with agents in development to trigger extrinsic apoptosis via TRAIL signalling, or to prevent the anti-apoptotic activity of BCL-2 proteins or inhibitor of apoptosis (IAP) proteins. Although the evasion o...

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Detalles Bibliográficos
Autores principales: Fox, Joanna L, MacFarlane, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931361/
https://www.ncbi.nlm.nih.gov/pubmed/27140313
http://dx.doi.org/10.1038/bjc.2016.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931361/
https://www.ncbi.nlm.nih.gov/pubmed/27140313
http://dx.doi.org/10.1038/bjc.2016.111

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