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Legionella pneumophila Carbonic Anhydrases: Underexplored Antibacterial Drug Targets

Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes which catalyze the hydration of carbon dioxide to bicarbonate and protons. Many pathogenic bacteria encode such enzymes belonging to the α-, β-, and/or γ-CA families. In the last decade, enzymes from some of these pathogens, including Legionel...

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Detalles Bibliográficos
Autor principal: Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931395/
https://www.ncbi.nlm.nih.gov/pubmed/27322334
http://dx.doi.org/10.3390/pathogens5020044