Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert(−/−) mice

The role of telomerase reverse transcriptase (TERT) has been extensively investigated in the contexts of aging and cancer. Interestingly, Tert(−/−) mice exhibit additional but unexpected aggressive and depressive behaviors, implying the potential involvement of TERT function in mood control. Our con...

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Detalles Bibliográficos
Autores principales: Zhou, Q-G, Wu, H-Y, Zhou, H, Liu, M-Y, Lee, H-W, Liu, X, Devkota, S, Ro, E J, Zhu, D-Y, Suh, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931604/
https://www.ncbi.nlm.nih.gov/pubmed/27300262
http://dx.doi.org/10.1038/tp.2016.106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931604/
https://www.ncbi.nlm.nih.gov/pubmed/27300262
http://dx.doi.org/10.1038/tp.2016.106

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