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CACNA1C hypermethylation is associated with bipolar disorder

The CACNA1C gene, encoding a subunit of the L-type voltage-gated calcium channel is one of the best-supported susceptibility genes for bipolar disorder (BD). Genome-wide association studies have identified a cluster of non-coding single-nucleotide polymorphisms (SNPs) in intron 3 to be highly associ...

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Detalles Bibliográficos
Autores principales: Starnawska, A, Demontis, D, Pen, A, Hedemand, A, Nielsen, A L, Staunstrup, N H, Grove, J, Als, T D, Jarram, A, O'Brien, N L, Mors, O, McQuillin, A, Børglum, A D, Nyegaard, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931616/
https://www.ncbi.nlm.nih.gov/pubmed/27271857
http://dx.doi.org/10.1038/tp.2016.99