Effects of KLK Peptide on Adjuvanticity of Different ODN Sequences

Endosomal Toll-like receptors (TLR) such as TLR3, 7, 8 and 9 recognize pathogen associated nucleic acids. While DNA sequence does influence degree of binding to and activation of TLR9, it also appears to influence the ability of the ligand to reach the intracellular endosomal compartment. The KLK (K...

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Detalles Bibliográficos
Autores principales: Chikh, Ghania, Luu, Rachel, Patel, Shobhna, Davis, Heather L., Weeratna, Risini D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931631/
https://www.ncbi.nlm.nih.gov/pubmed/27153098
http://dx.doi.org/10.3390/vaccines4020014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931631/
https://www.ncbi.nlm.nih.gov/pubmed/27153098
http://dx.doi.org/10.3390/vaccines4020014

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