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IVIg attenuates complement and improves spinal cord injury outcomes in mice
OBJECTIVE: Traumatic spinal cord injury (SCI) elicits immediate neural cell death, axonal damage, and disruption of the blood–spinal cord barrier, allowing circulating immune cells and blood proteins into the spinal parenchyma. The inflammatory response to SCI involves robust complement system activ...
Autores principales: | Brennan, Faith H., Kurniawan, Nyoman D., Vukovic, Jana, Bartlett, Perry F., Käsermann, Fabian, Arumugam, Thiruma V., Basta, Milan, Ruitenberg, Marc J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931715/ https://www.ncbi.nlm.nih.gov/pubmed/27386499 http://dx.doi.org/10.1002/acn3.318 |
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