MMP-9 overexpression is associated with intragenic hypermethylation of MMP9 gene in melanoma

Tumor spreading is associated with the degradation of extracellular matrix proteins, mediated by the overexpression of matrix metalloproteinase 9 (MMP-9). Although, such overexpression was linked to epigenetic promoter methylation, the role of intragenic methylation was not clarified yet. Melanoma w...

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Detalles Bibliográficos
Autores principales: Falzone, Luca, Salemi, Rossella, Travali, Salvatore, Scalisi, Aurora, McCubrey, James A., Candido, Saverio, Libra, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931845/
https://www.ncbi.nlm.nih.gov/pubmed/27115178
http://dx.doi.org/10.18632/aging.100951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931845/
https://www.ncbi.nlm.nih.gov/pubmed/27115178
http://dx.doi.org/10.18632/aging.100951

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