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MMP-9 overexpression is associated with intragenic hypermethylation of MMP9 gene in melanoma
Tumor spreading is associated with the degradation of extracellular matrix proteins, mediated by the overexpression of matrix metalloproteinase 9 (MMP-9). Although, such overexpression was linked to epigenetic promoter methylation, the role of intragenic methylation was not clarified yet. Melanoma w...
Autores principales: | Falzone, Luca, Salemi, Rossella, Travali, Salvatore, Scalisi, Aurora, McCubrey, James A., Candido, Saverio, Libra, Massimo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931845/ https://www.ncbi.nlm.nih.gov/pubmed/27115178 http://dx.doi.org/10.18632/aging.100951 |
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