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Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures

Aging is reflected by highly reproducible DNA methylation (DNAm) changes that open new perspectives for estimation of chronological age in legal medicine. DNA can be harvested non-invasively from cells at the inside of a person's cheek using buccal swabs – but these specimens resemble heterogen...

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Detalles Bibliográficos
Autores principales: Eipel, Monika, Mayer, Felix, Arent, Tanja, Ferreira, Marcelo R. P., Birkhofer, Carina, Gerstenmaier, Uwe, Costa, Ivan G., Ritz-Timme, Stefanie, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931852/
https://www.ncbi.nlm.nih.gov/pubmed/27249102
http://dx.doi.org/10.18632/aging.100972