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Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures
Aging is reflected by highly reproducible DNA methylation (DNAm) changes that open new perspectives for estimation of chronological age in legal medicine. DNA can be harvested non-invasively from cells at the inside of a person's cheek using buccal swabs – but these specimens resemble heterogen...
Autores principales: | Eipel, Monika, Mayer, Felix, Arent, Tanja, Ferreira, Marcelo R. P., Birkhofer, Carina, Gerstenmaier, Uwe, Costa, Ivan G., Ritz-Timme, Stefanie, Wagner, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931852/ https://www.ncbi.nlm.nih.gov/pubmed/27249102 http://dx.doi.org/10.18632/aging.100972 |
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