SIRT6 protects against endothelial dysfunction and atherosclerosis in mice

SIRT6 is an important member of sirtuin family that represses inflammation, aging and DNA damage, three of which are causing factors for endothelial dysfunction. SIRT6 expression is decreased in atherosclerotic lesions from ApoE(−/−) mice and human patients. However, the role of SIRT6 in regulating...

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Detalles Bibliográficos
Autores principales: Xu, Suowen, Yin, Meimei, Koroleva, Marina, Mastrangelo, Michael A., Zhang, Wenbo, Bai, Peter, Little, Peter J., Jin, Zheng Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931854/
https://www.ncbi.nlm.nih.gov/pubmed/27249230
http://dx.doi.org/10.18632/aging.100975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931854/
https://www.ncbi.nlm.nih.gov/pubmed/27249230
http://dx.doi.org/10.18632/aging.100975

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