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Lack of collagen VI promotes neurodegeneration by impairing autophagy and inducing apoptosis during aging
Collagen VI is an extracellular matrix (ECM) protein with a broad distribution in different tissues and mostly deposited at the close periphery of the cell surface. Previous studies revealed that collagen VI protects neurons from the toxicity of amyloid-βpeptides and from UV-induced damage. However,...
Autores principales: | Cescon, Matilde, Chen, Peiwen, Castagnaro, Silvia, Gregorio, Ilaria, Bonaldo, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931855/ https://www.ncbi.nlm.nih.gov/pubmed/27060109 http://dx.doi.org/10.18632/aging.100924 |
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