The linear ubiquitin-specific deubiquitinase Gumby/Fam105b regulates angiogenesis

A complex interplay of signaling events, including the Wnt pathway, regulates sprouting of blood vessels from preexisting vasculature during angiogenesis. Here we show that two distinct mutations in the (uro)chordate-specific Gumby/Fam105b gene cause an embryonic angiogenic phenotype in gumby mice....

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Detalles Bibliográficos
Autores principales: Rivkin, Elena, Almeida, Stephanie M., Ceccarelli, Derek F., Juang, Yu-Chi, MacLean, Teresa A., Srikumar, Tharan, Huang, Hao, Dunham, Wade H., Fukumura, Ryutaro, Xie, Gang, Gondo, Yoichi, Raught, Brian, Gingras, Anne-Claude, Sicheri, Frank, Cordes, Sabine P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931916/
https://www.ncbi.nlm.nih.gov/pubmed/23708998
http://dx.doi.org/10.1038/nature12296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931916/
https://www.ncbi.nlm.nih.gov/pubmed/23708998
http://dx.doi.org/10.1038/nature12296

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