ASSOCIATION BETWEEN GENETIC VARIANTS IN THE HNF4A GENE AND CHILDHOOD-ONSET CROHN’S DISEASE

BACKGROUND: Hepatocyte nuclear 4 alpha (HNF4α), involved in glucose and lipid metabolism, has been linked to intestinal inflammation and abnormal mucosal permeability. Moreover, in a genome-wide association study, the HNF4A locus has been associated with ulcerative colitis. The objective of our stud...

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Detalles Bibliográficos
Autores principales: Marcil, Valerie, Sinnett, Daniel, Seidman, Ernest, Boudreau, François, Gendron, Fernand-Pierre, Beaulieu, Jean-François, Menard, Daniel, Lambert, Marie, Bitton, Alain, Sanchez, Rocio, Amre, Devendra, Levy, Emile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931920/
https://www.ncbi.nlm.nih.gov/pubmed/22914433
http://dx.doi.org/10.1038/gene.2012.37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931920/
https://www.ncbi.nlm.nih.gov/pubmed/22914433
http://dx.doi.org/10.1038/gene.2012.37

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