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Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins

Interferon-induced proteins with tetratricopeptide repeats (IFITs) are innate immune effector molecules that are thought to confer antiviral defence through disruption of protein–protein interactions in the host translation-initiation machinery. However, it was recently discovered that IFITs can dir...

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Detalles Bibliográficos
Autores principales: Abbas, Yazan M., Pichlmair, Andreas, Górna, Maria W., Superti-Furga, Giulio, Nagar, Bhushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931921/
https://www.ncbi.nlm.nih.gov/pubmed/23334420
http://dx.doi.org/10.1038/nature11783