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Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins
Interferon-induced proteins with tetratricopeptide repeats (IFITs) are innate immune effector molecules that are thought to confer antiviral defence through disruption of protein–protein interactions in the host translation-initiation machinery. However, it was recently discovered that IFITs can dir...
Autores principales: | Abbas, Yazan M., Pichlmair, Andreas, Górna, Maria W., Superti-Furga, Giulio, Nagar, Bhushan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931921/ https://www.ncbi.nlm.nih.gov/pubmed/23334420 http://dx.doi.org/10.1038/nature11783 |
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