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Identification of a lupus-susceptibility locus leading to impaired clearance of apoptotic debris on New Zealand Black chromosome 13

Systemic lupus erythematosus is a chronic multi-organ autoimmune disease marked mainly by the production of anti-nuclear antibodies. Nuclear antigens become accessible to the immune system following apoptosis and defective clearance of apoptotic debris has been shown in several knockout mouse models...

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Detalles Bibliográficos
Autores principales: Pau, Evelyn, Loh, Christina, Minty, Gillian E.S., Chang, Nan-Hua, Wither, Joan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931923/
https://www.ncbi.nlm.nih.gov/pubmed/23328841
http://dx.doi.org/10.1038/gene.2012.64