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Identification of a lupus-susceptibility locus leading to impaired clearance of apoptotic debris on New Zealand Black chromosome 13
Systemic lupus erythematosus is a chronic multi-organ autoimmune disease marked mainly by the production of anti-nuclear antibodies. Nuclear antigens become accessible to the immune system following apoptosis and defective clearance of apoptotic debris has been shown in several knockout mouse models...
Autores principales: | Pau, Evelyn, Loh, Christina, Minty, Gillian E.S., Chang, Nan-Hua, Wither, Joan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931923/ https://www.ncbi.nlm.nih.gov/pubmed/23328841 http://dx.doi.org/10.1038/gene.2012.64 |
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