KDM2B/FBXL10 targets c-Fos for ubiquitylation and degradation in response to mitogenic stimulation

KDM2B (also known as FBXL10) controls stem cell self-renewal, somatic cell reprogramming and senescence, and tumorigenesis. KDM2B contains multiple functional domains, including a JmjC domain that catalyzes H3K36 demethylation and a CxxC zing finger that recognizes CpG islands and recruits the polyc...

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Detalles Bibliográficos
Autores principales: Han, Xiao-Ran, Zha, Zhengyu, Yuan, Hai-Xin, Feng, Xu, Xia, Yu-Kun, Lei, Qun-Ying, Guan, Kun-Liang, Xiong, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931990/
https://www.ncbi.nlm.nih.gov/pubmed/26725323
http://dx.doi.org/10.1038/onc.2015.482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931990/
https://www.ncbi.nlm.nih.gov/pubmed/26725323
http://dx.doi.org/10.1038/onc.2015.482

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