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KDM2B/FBXL10 targets c-Fos for ubiquitylation and degradation in response to mitogenic stimulation

KDM2B (also known as FBXL10) controls stem cell self-renewal, somatic cell reprogramming and senescence, and tumorigenesis. KDM2B contains multiple functional domains, including a JmjC domain that catalyzes H3K36 demethylation and a CxxC zing finger that recognizes CpG islands and recruits the polyc...

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Detalles Bibliográficos
Autores principales:	Han, Xiao-Ran, Zha, Zhengyu, Yuan, Hai-Xin, Feng, Xu, Xia, Yu-Kun, Lei, Qun-Ying, Guan, Kun-Liang, Xiong, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931990/ https://www.ncbi.nlm.nih.gov/pubmed/26725323 http://dx.doi.org/10.1038/onc.2015.482

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