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Decoding options and accuracy of translation of developmentally regulated UUA codon in Streptomyces: bioinformatic analysis

BACKGROUND: The gene bldA for leucyl [Formula: see text] is known for almost 30 years as a key regulator of morphogenesis and secondary metabolism in genus Streptomyces. Codon UUA is the rarest one in Streptomyces genomes and is present exclusively in genes with auxiliary functions. Delayed accumula...

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Detalles Bibliográficos
Autores principales: Rokytskyy, Ihor, Koshla, Oksana, Fedorenko, Victor, Ostash, Bohdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932002/
https://www.ncbi.nlm.nih.gov/pubmed/27429891
http://dx.doi.org/10.1186/s40064-016-2683-6