Treatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC–MS metabolomics

INTRODUCTION: Obestatin is a controversial gastrointestinal peptide purported to have metabolic actions. OBJECTIVES: This study investigated whether treatment with a stable obestatin analogue (PEG-OB(Cys(10), Cys(13))) changed plasma metabolite levels firstly in lean and subsequently in diet-induced...

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Detalles Bibliográficos
Autores principales: Cowan, Elaine, Kumar, Praveen, Burch, Kerry J., Grieve, David J., Green, Brian D., Graham, Stewart F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932145/
https://www.ncbi.nlm.nih.gov/pubmed/27471436
http://dx.doi.org/10.1007/s11306-016-1063-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932145/
https://www.ncbi.nlm.nih.gov/pubmed/27471436
http://dx.doi.org/10.1007/s11306-016-1063-0

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