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Treatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC–MS metabolomics
INTRODUCTION: Obestatin is a controversial gastrointestinal peptide purported to have metabolic actions. OBJECTIVES: This study investigated whether treatment with a stable obestatin analogue (PEG-OB(Cys(10), Cys(13))) changed plasma metabolite levels firstly in lean and subsequently in diet-induced...
Autores principales: | Cowan, Elaine, Kumar, Praveen, Burch, Kerry J., Grieve, David J., Green, Brian D., Graham, Stewart F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932145/ https://www.ncbi.nlm.nih.gov/pubmed/27471436 http://dx.doi.org/10.1007/s11306-016-1063-0 |
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