Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins

Inflammasomes are cytosolic molecular platforms that alert the immune system about the presence of infection. Here we report that zebrafish guanylate-binding protein 4 (Gbp4), an IFNγ-inducible GTPase protein harbouring a C-terminal CARD domain, is required for the inflammasome-dependent clearance o...

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Detalles Bibliográficos
Autores principales: Tyrkalska, Sylwia D., Candel, Sergio, Angosto, Diego, Gómez-Abellán, Victoria, Martín-Sánchez, Fátima, García-Moreno, Diana, Zapata-Pérez, Rubén, Sánchez-Ferrer, Álvaro, Sepulcre, María P., Pelegrín, Pablo, Mulero, Victoriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932187/
https://www.ncbi.nlm.nih.gov/pubmed/27363812
http://dx.doi.org/10.1038/ncomms12077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932187/
https://www.ncbi.nlm.nih.gov/pubmed/27363812
http://dx.doi.org/10.1038/ncomms12077

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