The landscape of chromosomal aberrations in breast cancer mouse models reveals driver-specific routes to tumorigenesis

Aneuploidy and copy-number alterations (CNAs) are a hallmark of human cancer. Although genetically engineered mouse models (GEMMs) are commonly used to model human cancer, their chromosomal landscapes remain underexplored. Here we use gene expression profiles to infer CNAs in 3,108 samples from 45 m...

Descripción completa

Detalles Bibliográficos
Autores principales: Ben-David, Uri, Ha, Gavin, Khadka, Prasidda, Jin, Xin, Wong, Bang, Franke, Lude, Golub, Todd R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932194/
https://www.ncbi.nlm.nih.gov/pubmed/27374210
http://dx.doi.org/10.1038/ncomms12160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932194/
https://www.ncbi.nlm.nih.gov/pubmed/27374210
http://dx.doi.org/10.1038/ncomms12160

Ejemplares similares