The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model

A central question in Alzheimer's Disease (AD) is whether the neuritic plaque is necessary and sufficient for the development of tau pathology. Hyperphosphorylation of tau is found within dystrophic neurites surrounding β-amyloid deposits in AD mouse models but the pathological conversion of ta...

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Detalles Bibliográficos
Autores principales: Li, Tong, Braunstein, Kerstin E., Zhang, Juhong, Lau, Ashley, Sibener, Leslie, Deeble, Christopher, Wong, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932197/
https://www.ncbi.nlm.nih.gov/pubmed/27373369
http://dx.doi.org/10.1038/ncomms12082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932197/
https://www.ncbi.nlm.nih.gov/pubmed/27373369
http://dx.doi.org/10.1038/ncomms12082

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