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The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model

A central question in Alzheimer's Disease (AD) is whether the neuritic plaque is necessary and sufficient for the development of tau pathology. Hyperphosphorylation of tau is found within dystrophic neurites surrounding β-amyloid deposits in AD mouse models but the pathological conversion of ta...

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Detalles Bibliográficos
Autores principales:	Li, Tong, Braunstein, Kerstin E., Zhang, Juhong, Lau, Ashley, Sibener, Leslie, Deeble, Christopher, Wong, Philip C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932197/ https://www.ncbi.nlm.nih.gov/pubmed/27373369 http://dx.doi.org/10.1038/ncomms12082

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