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Paracoccin Induces M1 Polarization of Macrophages via Interaction with TLR4

The fungal human pathogen Paracoccidioides brasiliensis contains paracoccin (PCN), a multi-domain protein that has lectin and N-acetyl-glucosaminidase activities, which account for its effects on the growth and morphogenesis of the fungus and on the activation of host macrophages through its interac...

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Detalles Bibliográficos
Autores principales: Freitas, Mateus S., Oliveira, Aline F., da Silva, Thiago A., Fernandes, Fabrício F., Gonçales, Relber A., Almeida, Fausto, Roque-Barreira, Maria C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932198/
https://www.ncbi.nlm.nih.gov/pubmed/27458431
http://dx.doi.org/10.3389/fmicb.2016.01003