SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes

RAB10 is a regulator of insulin-stimulated translocation of the GLUT4 glucose transporter to the plasma membrane (PM) of adipocytes, which is essential for whole-body glucose homeostasis. We establish SEC16A as a novel RAB10 effector in this process. Colocalization of SEC16A with RAB10 is augmented...

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Detalles Bibliográficos
Autores principales: Bruno, Joanne, Brumfield, Alexandria, Chaudhary, Natasha, Iaea, David, McGraw, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932369/
https://www.ncbi.nlm.nih.gov/pubmed/27354378
http://dx.doi.org/10.1083/jcb.201509052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932369/
https://www.ncbi.nlm.nih.gov/pubmed/27354378
http://dx.doi.org/10.1083/jcb.201509052

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