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Self-Assembly of Amphiphilic Dendrimers: The Role of Generation and Alkyl Chain Length in siRNA Interaction

An ideal nucleic-acid transfection system should combine the physical and chemical characteristics of cationic lipids and linear polymers to decrease cytotoxicity and uptake limitations. Previous research described new types of carriers termed amphiphilic dendrimers (ADs), which are based on polyami...

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Detalles Bibliográficos
Autores principales: Márquez-Miranda, Valeria, Araya-Durán, Ingrid, Camarada, María Belén, Comer, Jeffrey, Valencia-Gallegos, Jesús A., González-Nilo, Fernando Danilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932498/
https://www.ncbi.nlm.nih.gov/pubmed/27377641
http://dx.doi.org/10.1038/srep29436