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Realization of tristability in a multiplicatively coupled dual-loop genetic network

Multistability is a crucial recurring theme in cell signaling. Multistability is attributed to the presence of positive feedback loops, but the general condition and essential mechanism for realizing multistability remain unclear. Here, we build a generic circuit model comprising two transcription f...

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Detalles Bibliográficos
Autores principales: Huang, Bo, Xia, Yun, Liu, Feng, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932522/
https://www.ncbi.nlm.nih.gov/pubmed/27378101
http://dx.doi.org/10.1038/srep28096