Alkanediamide-Linked Bisbenzamidines Are Promising Antiparasitic Agents

A series of 15 alkanediamide-linked bisbenzamidines and related analogs was synthesized and tested in vitro against two Trypanosoma brucei (T.b.) subspecies: T.b. brucei and T.b. rhodesiense, Trypanosoma cruzi, Leishmania donovani and two Plasmodium falciparum subspecies: a chloroquine-sensitive str...

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Detalles Bibliográficos
Autores principales: Vanden Eynde, Jean J., Mayence, Annie, Mottamal, Madhusoodanan, Bacchi, Cyrus J., Yarlett, Nigel, Kaiser, Marcel, Brun, Reto, Huang, Tien L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932538/
https://www.ncbi.nlm.nih.gov/pubmed/27104545
http://dx.doi.org/10.3390/ph9020020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932538/
https://www.ncbi.nlm.nih.gov/pubmed/27104545
http://dx.doi.org/10.3390/ph9020020

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