Development of a New Radiofluorinated Quinoline Analog for PET Imaging of Phosphodiesterase 5 (PDE5) in Brain

Phosphodiesterases (PDEs) are enzymes that play a major role in cell signalling by hydrolysing the secondary messengers cyclic adenosine monophosphate (cAMP) and/or cyclic guanosine monophosphate (cGMP) throughout the body and brain. Altered cyclic nucleotide-mediated signalling has been associated...

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Detalles Bibliográficos
Autores principales: Liu, Jianrong, Wenzel, Barbara, Dukic-Stefanovic, Sladjana, Teodoro, Rodrigo, Ludwig, Friedrich-Alexander, Deuther-Conrad, Winnie, Schröder, Susann, Chezal, Jean-Michel, Moreau, Emmanuel, Brust, Peter, Maisonial-Besset, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932540/
https://www.ncbi.nlm.nih.gov/pubmed/27110797
http://dx.doi.org/10.3390/ph9020022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932540/
https://www.ncbi.nlm.nih.gov/pubmed/27110797
http://dx.doi.org/10.3390/ph9020022

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