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Evaluating the Role of p38 MAPK in the Accelerated Cell Senescence of Werner Syndrome Fibroblasts

Progeroid syndromes show features of accelerated ageing and are used as models for human ageing, of which Werner syndrome (WS) is one of the most widely studied. WS fibroblasts show accelerated senescence that may result from p38 MAP kinase activation since it is prevented by the p38 inhibitor SB203...

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Detalles Bibliográficos
Autores principales: Davis, Terence, Brook, Amy J. C., Rokicki, Michal J., Bagley, Mark C., Kipling, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932541/
https://www.ncbi.nlm.nih.gov/pubmed/27136566
http://dx.doi.org/10.3390/ph9020023