Chemical Variations on the p53 Reactivation Theme

Among the tumor suppressor genes, p53 is one of the most studied. It is widely regarded as the “guardian of the genome”, playing a major role in carcinogenesis. In fact, direct inactivation of the TP53 gene occurs in more than 50% of malignancies, and in tumors that retain wild-type p53 status, its...

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Detalles Bibliográficos
Autores principales: Ribeiro, Carlos J. A., Rodrigues, Cecília M. P., Moreira, Rui, Santos, Maria M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932543/
https://www.ncbi.nlm.nih.gov/pubmed/27187415
http://dx.doi.org/10.3390/ph9020025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932543/
https://www.ncbi.nlm.nih.gov/pubmed/27187415
http://dx.doi.org/10.3390/ph9020025

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