Improved Aptamers for the Diagnosis and Potential Treatment of HER2-Positive Cancer

Aptamers provide a potential source of alternative targeting molecules for existing antibody diagnostics and therapeutics. In this work, we selected novel DNA aptamers targeting the HER2 receptor by an adherent whole-cell SELEX approach. Individual aptamers were identified by next generation sequenc...

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Detalles Bibliográficos
Autores principales: Gijs, Marlies, Penner, Gregory, Blackler, Garth B., Impens, Nathalie R.E.N., Baatout, Sarah, Luxen, André, Aerts, An M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932547/
https://www.ncbi.nlm.nih.gov/pubmed/27213406
http://dx.doi.org/10.3390/ph9020029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932547/
https://www.ncbi.nlm.nih.gov/pubmed/27213406
http://dx.doi.org/10.3390/ph9020029

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