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Synthesis and Pharmacological Properties of Novel Esters Based on Monocyclic Terpenes and GABA
Novel esters of γ-aminobutyric acid (GABA) with monocyclic terpenes were synthesized via Steglich esterification and characterized by (1)H-NMR, IR and mass spectral studies. Their anticonvulsant, analgesic and anti-inflammatory activities were evaluated by a PTZ-induced convulsion model, AITC-induce...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932550/ https://www.ncbi.nlm.nih.gov/pubmed/27304960 http://dx.doi.org/10.3390/ph9020032 |