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Tumor Heterogeneity, Single-Cell Sequencing, and Drug Resistance

Tumor heterogeneity has been compared with Darwinian evolution and survival of the fittest. The evolutionary ecosystem of tumors consisting of heterogeneous tumor cell populations represents a considerable challenge to tumor therapy, since all genetically and phenotypically different subpopulations...

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Detalles Bibliográficos
Autores principales: Schmidt, Felix, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932551/
https://www.ncbi.nlm.nih.gov/pubmed/27322289
http://dx.doi.org/10.3390/ph9020033