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Tumor Heterogeneity, Single-Cell Sequencing, and Drug Resistance
Tumor heterogeneity has been compared with Darwinian evolution and survival of the fittest. The evolutionary ecosystem of tumors consisting of heterogeneous tumor cell populations represents a considerable challenge to tumor therapy, since all genetically and phenotypically different subpopulations...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932551/ https://www.ncbi.nlm.nih.gov/pubmed/27322289 http://dx.doi.org/10.3390/ph9020033 |