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Characterization of a Dmd(EGFP) reporter mouse as a tool to investigate dystrophin expression

BACKGROUND: Dystrophin is a rod-shaped cytoplasmic protein that provides sarcolemmal stability as a structural link between the cytoskeleton and the extracellular matrix via the dystrophin-associated protein complex (DAPC). Mutations in the dystrophin-encoding DMD gene cause X-linked dystrophinopath...

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Detalles Bibliográficos
Autores principales: Petkova, Mina V., Morales-Gonzales, Susanne, Relizani, Karima, Gill, Esther, Seifert, Franziska, Radke, Josefine, Stenzel, Werner, Garcia, Luis, Amthor, Helge, Schuelke, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932663/
https://www.ncbi.nlm.nih.gov/pubmed/27382459
http://dx.doi.org/10.1186/s13395-016-0095-5