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Dual function of partitioning-defective 3 in the regulation of YAP phosphorylation and activation

Partitioning-defective 3 (Par3), a key component of the evolutionarily conserved polarity PAR complex (Par3/Par6/aPKC), controls cell polarity and contributes to cell migration, proliferation and tumor development. Emerging evidence indicates that cell polarity proteins function as upstream modulato...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Wang, Shuting, Wang, Sai, Qiao, Jing, Zhang, Lei, Zhang, Zhe, Chen, Zhengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932730/
https://www.ncbi.nlm.nih.gov/pubmed/27462467
http://dx.doi.org/10.1038/celldisc.2016.21