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Phenotypic research on senile osteoporosis caused by SIRT6 deficiency

Osteoporosis is a serious public bone metabolic disease. However, the mechanisms underlying bone loss combined with ageing, which is known as senile osteoporosis, remains unknown. Here we show the detailed phenotype of this disease caused by SIRT6 knock out (KO) in mice. To the best of our knowledge...

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Detalles Bibliográficos
Autores principales: Zhang, De-Mao, Cui, Di-Xin, Xu, Ruo-Shi, Zhou, Ya-Chuan, Zheng, Li-Wei, Liu, Peng, Zhou, Xue-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932771/
https://www.ncbi.nlm.nih.gov/pubmed/27357320
http://dx.doi.org/10.1038/ijos.2015.57